母乳低聚糖 6'-SL（6'-唾液酸乳糖 ) 是母乳中最丰富的唾液酸化HMO。
健康益处和研究
6′-SL的具体功能益处包括降低有害菌及其蛋白质的黏附风险1, 2, 3。唾液酸是神经元的重要组成部分4，3′-SL 和 6′-SL通过提供唾液酸特别支持婴儿大脑发育。
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1 Simon et al. “Inhibition of Helicobacter pylori binding to gastrointestinal epithelial cells by sialic acid-containing oligosaccharides.” Infect Immun.2(1997): 750–757.
2 Amr El-Hawiet, Elena N Kitova, John S Klassen, “Recognition of human milk oligosaccharides by bacterial exotoxins”. Glycobiology, Volume 25, Issue 8, (2015): 845–854.
3 Hester et al. “Human milk oligosaccharides inhibit rotavirus infectivity invitro and in acutely infected piglets.” J. Nutr. 110.7 (2013): 1233−42.
4 Wang B. “Molecular Mechanism Underlying Sialic Acid as an Essential Nutrient for Brain Development and Cognition.” Nutrition, 1.3 (2012): 465S-472S.